Словарь морфологических терминов — Morphology Terms Dictionary — Словник морфологічних термінів
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Elastin - Эластин - Еластин

Elastin
Эластин
Еластин

 
ELASTIN G. elastikos = impulsive (as in elastic recoil);
protein component of yellow fibres of elastic tissue.
ELASTIN is a protein that exists as fibers in the extracellular spaces of many connective tissues. Elastin derives its name from its ability to act as an elastic band, i. e., to stretch and recoil with transient force. It is located throughout many tissues and organs of higher vertebrates and plays an important functional role in maintaining pressures associated with liquid and air flow in the cardiovascular and pulmonary systems. Elastogenic cells synthesize and secrete a soluble monomeric form of elastin into the extracellular space. The enzyme, lysyl oxidase, initiates cross-linking of the soluble monomers into insoluble fibers. Extracellular elastin associates closely with other proteins in the matrix including microfibrillar proteins and collagens. Once laid down in the matrix, the insoluble protein is very stable and resistant to degradation. Because of its critical role in the normal development and function of vital organs, impairment of elastin synthesis or proteolytic degradation of the insoluble fibers results in major clinical pathologies.

The polypeptide chain contains appropriately 850 amino acids and a molecular mass of 65–72 kDa. The actual size varies somewhat among different species. Glycine (33%), alanine (18%), proline (13%), valine (17%), and leucine (5%) residues represent 86% of the total amino acids. Prolyl hydroxylase converts 1–2% of the proline residues to hydroxyproline.
(© Judith Ann Foster)


ЭЛАСТИН — глобулярный белок, входящий в состав эластических волокон (обладающих эластичностью и позволяющих тканям восстанавливать форму).

См. лекции Соединительные ткани.

 
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Key words: Medical Dictionary Glossary, Histological and Embryological terms, Life Science, health, Scientific terminology, Molecular Biology & Cytology. Ключевые слова: Словарь, значение, медицинский словарь терминов; Довідник справочник морфологических терминов. Относится к здравоохранению и здоровью человека и животных. Анатомия, гистология, эмбриология, цитология.
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