Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Pigmental form of the lichen planus: clinical-morphological parallels Пігментна форма червоного плоского лишаю: клініко-гістологічні паралелі 5 10 UK T. V. Svyatenko 2008 8 14 2008 9 18 In article are described results of own supervision over patients pigmental by the form lichen ruber planus (LP) which is the atypical form of defeat of a skin and mucous membranes. Modern methods of research have allowed the author to approach from new positions to studying pigmental LP and to define a role tissue changes in pathogenesis of dermatosis. By the author it is studied clinical, pathomorphology and immunohistochemical features pigmental forms LP. Under supervision was 10 patients with pigmental form LP. The analysis of results of the lead morphological researches the amazed skin has revealed infringement of processes keratinisation, dystrophic and proliferation changes in epidermis, inflammatory changes in derma, presence except lymphohistiocytes elements, and numerous melanophags with the considerable maintenance of a pigment in cytoplasm. At carrying out immunohistochemical researches by the author it is obtained following data: Significant amount CD68 + cages macrophagals a number in a zone expressed infiltrations of derma, typical granularical cytoplasmatic character of colouring. On the basis of the lead researches it is possible to approve, that diagnostics pigmental forms LP which differs clinical polymorphism, that should be based on complex studying macro-and microscopic picture of defeat in view of specific features dermatosis, that will allow different to approach to questions of purpose of treatment.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Morphological study of human heart and placenta in the first trimester of prenatal period of ontogenesis Морфологическое исследование сердца и плаценты человека в первом триместре пренатального периода онтогенеза 11 14 RU L. V. Abdul-Ogly 2008 8 12 2008 9 5 Probability of abnormal development is high in certain periods when the increased sensitiveness of embryo and fetus takes place. Influence of damaging factors as maternal infection and, consequently, fetal infection is a reason of abnormal development. Morphological characteristics of heart and placenta were studied during the first trimester of prenatal period of ontogenesis. 17 embryos, fetuses and placenta of 4-12 weeks were used. Abortions were made according to medical statements or maternal willing. The abnormal development of primary leaflets of atrioventricular valves, retardation of fetus growth, abnormal position of organs including ectopic heart, and abnormal limbs development were observed.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Medico-legal estimation of histological changes of myocardium of auricles at an oxymortia in the case of oxymortia from sharp ischemic heart trouble Судово-медична оцінка гістологічних змін міокарда передсердь у разі раптової смерті внаслідок гострої ішемічної хвороби серця 15 19 UK A. V. Dunaev 2008 7 10 2008 8 21 We determined the local changes during histological examination of auriclar myocardium in cases of sudden death from acute coronary insufficiency. In the areas of ischemia the diminishing in 1,5 time of specific volume of myocardium fibers took place, and also undulating deformation, fragmentation of cardiomyocytes, their loss of striates, hyperchromia and increasing of nuclear size, diminishing of specific volume of arteriolas, spasm and plasma saturation of arteriolar wall, plethora of capillaries from stasis of erythrocytes as «monetary columns», microthrombosis and plasma saturation of vein walls, increases of specific volume of veins. We suggest that all of these changes may be useful as histological criteria for differential diagnostics of sudden death from acute coronary insufficiency.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Blood supply of rat heart in normal condition and after sidnocarb treatment Кровопостачання серця щура в нормі та при дії сиднокарба 20 23 UK V. O. Kozlov O. L. Drozdov O. S. Koshelev M. Yu. Scharikov O. V. Kozlov 2008 8 18 2008 9 23 The aim of the research was to investigate the changes of vascular bed of rat heart in the normal condition and under sydnocarb treatment. The materials of our research were 22 rats, which were contained in the conditions of vivarium. By both anatomical and histological methods it was established, that rats have 3 types of supplement, and also delivering and feeding type of vessel branching. The delivering (87%) type of branching prevails in the walls of left ventricle of the heart and interventricular septa, where the diameter of vessels was relatively less, and the amount of branches was 3-4, that suggest the higher intensity of exchange of matters. The feeding type of branching (64%) prevails in the right ventricle and interatrial septa, where the amount of branches of the first order of branching was from 6 to 9. On early stages (to 3 days), after sydno-carb introduction, the change of vascular bed at the level of arteries and veins was accordingly the increase of their diameter on 10% and 27%.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Changes of peripheral blood under the influence of the electromagnetic radiation Зміни показників периферичної крові при дії електромагнітного випромінювання 24 26 UK V. V. Kocharniy 2008 8 11 2008 9 16 There are a lot of unsolved problems about the influence of electromagnetic radiation on different organs and systems, and also the study of influence of this factor on the biological environments of organism is actual. We have studied the influence of electromagnetic radiation on peripheral blood of normal and pregnant rats. The purpose was to study the changes of peripheral blood cells of normal and pregnant under the influence of electromagnetic radiation. 10 Vistar female rats of 4-6 month age, mass 180-250 g were used. Animals were distributed on 3 groups. The first group is the control, second - pregnant females which did not get the sessions of electromagnetic radiation, third - pregnant females which got the sessions of electromagnetic radiation. The sessions were made by the apparatus «Ramed-expert 02» with frequency 42,3 GHertz, exposition 30 min. daily, on the region of stomach and pelvis during 10 days. In a control group peripheral blood cells did not change substantially. The increase of stab and segmented neutrophils, and insignificant reduction in lymphocyte number in pregnant rats were observed. In pregnant animals which got the sessions of electromagnetic radiation, all indexes remained near the norm.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Dispersive two-factor analysis of the basic histomorphometric indicators of mesenteric lymph nodes of rats at parenteral injection of cerebrospinal fluid Дисперсионный двухфакторный анализ основных гисто-морфометрических показателей брыжеечных лимфатических узлов крыс при парентеральном введении спинномозговой жидкости 27 30 RU M. A. Kriventsov 2008 8 22 2008 9 23 The two-factorial dispersive analysis considering the fact and degree of influence of two signs (the scheme of parenteral injection of the cerebrospinal fluid and the ontogenetic period of the beginning of injection of the cerebrospinal fluid) on histomorphometric factors was carried out. The greatest influence of the factor of the age period on signs marked on 7 day of experiment whereas on 60 day of experiment the scheme of injection of the cerebrospinal fluid is defining.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Bone repair of the tibia in adult rats during hypoosmolar overhydratation Репаративний остеогенез великогомілкової кістки щурів зрілого віку в умовах гіпоосмолярної гіпергідрії легкого ступеня 31 36 UK M. Pogorelov V. 2008 7 27 2008 9 11 We studied futures of the tibia repair during overhydratation. We made tibia defect for 48 adult rats. Experimental group took "Minirin" (Ferring) for modeling overhydratation. We used hystologycal, morphometric, biochemical, SEM methods for studies of the bone repair. Was detected that experimental rats has disorders in cells ant tissues relationships but this is not change stages of the bone repair. In same time disorders of aqua balance lowers processes of the forming of the new bone tissue. Changes of the organic compartment didn't change mineral homeostasis of the hew bone that detected by SEM.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 A novel source of epicardium in birds: morphological observation Новый источник эпикарда у птиц: морфологическое наблюдениЕ 37 43 RU O. Yu. Pototskaya 2008 8 16 2008 9 20 The main source of epicardium in birds is proepicardium, which is situated on the right horn of the sinus venous, dorsally to atrio-ventricular groove. Recently one more source of epicardium was described, it was named pericardial proliferates, that give rise to the epicardium of the distal part of the outflow tract. But, after proepicardium photoablation, compensatory epicardium aroused from the ventral body wall, caudally to the heart. Thereby the goal of our work was to investigate proepicardium-like structures of the pericardial cavity in birds. Beginning from the 13 stage by HH we observed proepicar-dium-like structures, which in cellular composition were similar to proepicardium. They derived from the lateral plate meso-derm and were situated on the funnel of the anterior intestinal gate, along to one of the vitelline vein. On the 16/17 stage by HH vesicles, containing mesenchimal cells, was budding of from proepicardium-like structures and attached to the heart on the right side of atrio-ventricular groove and ventricular loop. Localization of the proepicardium-like structures in the place, where in mammalian septum transversum (the source of proepicardium in mammalian) forms, and also the possibility of proepicardium-like structures to form vesicles gave us an occasion to suggest, that proepicardium-like structures are homologous of mammalian proepicardium. It could be concluded only after further investigations.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 The features of human heart internal relief structure in prenatal ontogenesis Особливості будови внутрішнього рельєфу серця людини в пренатальному онтогенезі 44 46 UK О. О. Savenkova S. V. Kozlov А. А. Indzhykulyan 2008 7 6 2008 9 12 We have reviewed the development of internal relief of 101 human hearts during prenatal ontogenesis. It was used a macroscopic, immunohystochemical research methods, which enabled us to trace the processes of vessel’s development, proliferation of cardiac wall cells, heteromorphy of its structure in various stages of development. The data indicate the involvement of cardiogel, primary cardiomyocytes, as well as mesenchymal cells in the development and statement of the structural components, which form the internal relief of the heart chambers. The process of heart wall’s delamination is a separate morphological mechanism. Delamination plates are embryo material for the formation of tendinous chords, papillary muscles and muscle trabecula. Process of forming of the internal structures of relief occurs during the prenatal period of 5-20 weeks ontogenesis. One of the first parts of the heart, in which the process of papillary-trabecular apparatus forming occurs, is the atrium’s wall.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Histotopographic characteristics of the pancreatoduodenal organocomplex in fetuses and newborns Гістотопографічні особливості панкреатодуоденального органокомплексу в плодів та новонароджених 47 50 UK O. M. Slobodian 2008 8 14 2008 9 18 The object of the research was to establish a chronological order of the histotopography of the duodenum and pancreas during the perinatal period of ontogenesis. It has been established that the histostructure of the duodenal wall in early fetuses (4-5 months) is characterized by the availability of primary crypts, the muscular layer of the mucous tunic, variable thickness of the layers of the muscular coat and a feebly marked character of the serous tunic; in late fetuses (8-10 months) - by the forming of the villi of the mucous membrane, the presence of transparent goblet cells, Brunner’s glands in the submucous layer and an almost uniform thickness of the layers in the muscular tunic. The lobular structure of the pancreas becomes formed starting with the 5th-6th months of development. Goblet cells occur in the mucous tunic of the interlobular ducts and the main pancreatic duct in late fetuses and newborns. The islets of Langerhans in early fetuses make up 1.2-3.5% of the volume of the glandular component of the organ and distributed unevenly, 4.8-8.3% with a uniform distribution in late fetuses and newborns.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Histomorphometrical estimation of the organism hyperhydratation influence on bone tissues condition in young animals Гістоморфометрична оцінка впливу гіпергідратації організму на стан кісткової тканини у молодих тварин 51 55 UK G. F. Tkach 2008 7 22 2008 9 10 The purpose of the study - basing on morphological analysis to estimate the particularities of structural organization of proximal cartilage epiphysis of the shoulder bones in young animals, which were exposed to hyperhydratation conditions. According to comparative aspect, investigation of histomorphometrical parameters of bone tissue in young animal, that were exposed to water intoxication, was accompanied with oppression of bone formation, namely - narrowing of the proliferation zone (on 3,36 - 6,24%) and reduction in osteoblasts amount (3,33 - 5,37%). The other investigated parameters, change only because of the changes in above-mentioned parameters.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 The development of the orbital fasciae and cellular tissue spaces at an early stage of human ontogenesis Розвиток фасцій та клітковинних просторів очної ямки в ранньому періоді онтогенезу людини 56 59 UK A. A. Shkrobanets 2008 8 19 2008 9 23 The development of the orbital fasciae and cellular tissue spaces during the embryonic and prefetal periods of ontogenesis has been studied by means of the morphological research methods. It has been established that the said structures develop from the mesenchyme, surrounding the eyeballs germ and optic nerve. The forming of the cellular tissue spaces proceed simultaneously with the development of the orbital walls and the musculo-fascial complex of the oculomotor muscles and roughly takes shape by the end of the 10-th week. In the course of this period certain contents of the spaces and a topog-raphical arrangement of their components were formed.

Ukrainian Scientific Society of Anatomists, Histologists, Embryologists Morfologiâ 1997-9665 2 4 2009 1 22 Quantitative morphological estimation of surgical treatment of patients with a chronic ischemia of the lower limb with the direct, indirect and composite revascularization Кількісна морфологічна оцінка результатів хірургічного лікування хворих з хронічною ішемією нижньої кінцівки за допомогою прямої, непрямої і композитної реваскулярізації 60 71 UK V. M. Shkuropat I. V. Tverdokhleb M. F. Drjuk 2008 7 23 2008 9 2 The purpose of research was the morphological analysis of anterior tibial muscle after direct, indirect and composite revascularization in near-term and long-term postoperative periods. The biopsy material from 144 patients from 25 till 84 years with ІІІ degree ischemia of lower limb as a result of occlusive-stenotic disorders of arteries of femoral-popliteal-tibial segment. Patients have been divided into three groups: 1) 37 patients after femoral-tibial reconstruction; 2) 57 patients after indirect revascularisation with autotransplantation of bone marrow; 3) 50 patients after composite revascularization of distal part of lower limb. The observation was carried out in the near-term postoperative period and in 2 years. Research was carried out in age groups: І - till 34 years; ІІ - 35-59 years; ІІІ - 60-74 years; ІV - 75 years and more. Histological and mor-phometric study of tissue samplings of anterior tibial muscle taken between superior and middle one thirds was carried out. It have been determined that direct revascularisation causes the significant improvement in morphological parameters of muscular, stromal and microcirculate components of muscle in all age groups during 6 months after operation, however does not provide the stabilization of positive morphological changes in long-term postoperative period. Indirect revascularization does not change significally structurally-functional condition of components of muscle in near-term postoperative period, however causes the stable normalization of parameters of tissue components due to initiation of neovasculogenesis at patients till 75 years. Composite revascularization for these patients allows to receive near-term normalizing effect concerning the studied morphological criteria after operation and to provide its stabilization in the long-term postoperative period.